这是一部有机合成的重要参考书
[书 名] 有机合成大全(Comprehensive Organic Synthesis)
[作 者] 美国 加利福尼亚州 斯坦福大学 B.M.托斯特教授(Barry M. Trost Stanford University, Stanford, CA, USA)
英国 剑桥 剑桥大学 I.弗来明教授 (I. Fleming, University of Cambridge, Cambridge, UK)
[出版社] PERGAMON PRESS
[关键词] SYNTHESIS;ORGANIC CHEMISTRY
[分 类] 理工学科类>>化学>>有机化学
[版 本] First edition 1991 Reprinted 1993,1999,2002,2005,2006,2007
[ISBN号] ISBN- 0-08-035929-9 (set)
[内容简介] 共九卷,约500M.各种有机反应，几乎全都有，有明确的文献出处，有机合成必备.
[简介链接] http://www.elsevier.com/wps/find/bookvolume.cws_home/26507/vol1
[作者和他的小组]
[作者简介]美国斯坦福大学化学系Barry M. Trost 教授
Trost教授1965年在Massachusetts技术研究所取得博士学位，师从H. O. House教授。其后在美国国家科学委员会做博士后工作，1969年在Wisconsin大学成为化学教授，1987年作为化学教授进入斯坦福大学，目前是斯坦福大学人文及科学学校的Job and Tamaki教授。Trost教授杰出的化学成就还赢得了众多的科学奖项，包括ACS Award in Pure Chemistry （1977）、ACS Award for Creative Work in Synthetic Organic Chemistry (1981)、ACS Roger Adams Award (1995)、Presidential Green Chemistry Challenge Award（1998）、ACS Arthur C. Cope Award（2004）等。他在1980年和1982年分别被选为美国科学院和美国艺术和科学院院士。
Professor Trost’s work has been characterized by a very high order of imagination, innovation and
scholarship. He has ranged over the entire field of organic synthesis, particularly emphasizing
extraordinarily novel methodology. Further, he has repeatedly demonstrated how his innovative
methodology allows for the simplification of many complex target oriented syntheses leading to natural
products of high biological activity. Early in his career, Professor Trost participated in the isolation and
structure determination of the Cecropria Juvenile hormone. These studies helped to promulgate the
concept that insect growth regulators can serve as ecologically preferable alternatives to pesticides.
The long
term goal and defining mission of Professor Trost’s career has been toward enhancing synthetic
effectiveness. He has virtually created whole new methodologies and strategies in organic synthesis.
Among the areas which he has pioneered are the use of sulfur based reagents and transition metal, most
notably palladium, and more recently ruthenium, catalysts in complex setting. More recently, his work has
focused on enantioselective catalysts via the rational design of “chiral space.” This work requires a detailed
grasp of the mechanistic nuances of organometallic reactions. As part of this program, he designed a new
class of ligands that spontaneously forms dinuclear complexes that are proving to be especially effective at
asymmetric catalysis. Another continuing theme, directed to the realities of organic synthesis in fostering
commercial goals, is the strategy of “atom economy.” Thus, synthetic building blocks are combined to
produce complex targets in high yield with a bare minimum of debris under the guidance of carefully crafted
catalysts. In this way, organic synthesis can be brought to bear in process settings to reach substances of
high complexity in a commercially feasible way which minimizes environmental impact. Barry Trost’s
triumphs in total synthesis include complex terpenoids, steroids, alkaloids, vitamins, antibiotics,
nucleosides and macrolides. His syntheses are conducted with characteristic flair and serve as learning
resources in addressing the limits of the methodology which he tends to develop independently.
In recognition of his many contributions, Professor Trost has received a number of awards, including
the ACS Award in Pure Chemistry (1977), the ACS Award for Creative Work in Synthetic Organic Chemistry
(1981), the Baekeland Award (1981), the first Allan R. Day Award of the Philadelphia Organic Chemists' Club
(1983), the Chemical Pioneer Award of the American Institute of Chemists (1983), the Alexander von
Humboldt Stiftung Award (1984), MERIT Award of NIH (1988), Hamilton Award (1988), Arthur C. Cope
Scholar Award (1989), Guenther Award in the Chemistry of Essential Oils and Related Products (1990), the
Dr. Paul Janssen Prize (1990), the ASSU Graduate Teaching Award (1991), Pfizer Senior Faculty Award
(1992), Bing Teaching Award (1993), the ACS Roger Adams Award (1995), the Presidential Green Chemistry
2006年Barry M. Trost 教授，作为被中国科学院上海有机化学研究所邀请的贵宾，为“汪猷科学讲座” 分别两次向广大师生作了题为“Crafting Chiral Space for Asymmetric Induction in a Catalytic Synthetic Reaction: The Nucleophile”、“On Inventing Reactions for Atom Economy”的学术报告。Trost教授在有机所的学术演讲，内容精彩，整个报告大厅座无虚席。演讲后，他还走访了麻生明院士、丁奎岭、侯雪龙、唐勇等教授的课题组，对有机所实验设施、活跃的科学思维留下了良好的印象，加深了对有机所在中国有机化学领域突出地位的了解。此次访问中，Trost教授接受了姜标所长授予的 “中国科学院上海有机化学研究所名誉教授”的称号。
[作者和他的小组相关链接]
http://www.stanford.edu/group/bmtrost/
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本帖最后由 kawapu007 于 2008-3-8 10:24 编辑 ]
